International Conference on Applications of Mathematics to Nonlinear Sciences. Electron. J. Diff. Eqns., Conference 24 (2017), pp. 75-83.

2D model on heat regulation in human body with dermal tumor

Khalid Nazir, Mukhtar A. Khanday, Bashir A. Ganai

Abstract:
To predict the thermal fluctuations of a finite biological tissue in presence of tumor, an attempt has been made to formulate a 2D mathematical model based on the cross sectional temperature distribution in the tissues of the human limbs and variational finite element approach has been employed to establish the solution of the model. It is assumed that the dermal region of the human body is hosting tumor/cancerous cells. Thermal distribution at the tumor region with respect to different input parameters has been computed using MATLAB software. The physiological and bio-physical parameters like metabolic heat generation, blood mass flow rate and thermal conductivity are assumed to vary in the sub regions independently. The model describes the exchange of heat between the internal biological tissues and other surrounding media. Thermal fluctuations at the targeted regions were obtained with respect to various power densities of the heating sources. The results obtained may be helpful for various cases of practical interest especially in the treatment of cancerous tumors and in local hyperthermic therapies.

Published November 15, 2017.
Math Subject Classifications: 92B05, 92C10, 92C42.
Key Words: Thermoregulation; mathematical model; dermal tumor.

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Khalid Nazir
Department of Mathematics
University of Kashmir
Srinagar, Jammu and Kashmir, 190006, India
email: khldnzr99@gmail.com
Mukhtar A. Khanday
Department of Mathematics
University of Kashmir
Srinagar, Jammu and Kashmir, 190006, India
email: khanday@gmail.com
Bashir A. Ganai
CORD, University of Kashmir
Srinagar, Jammu and Kashmir, 190006, India
email: bbcganai@gmail.com

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