\documentclass[reqno]{amsart}
\usepackage{hyperref}

\AtBeginDocument{{\noindent\small
\emph{Electronic Journal of Differential Equations},
Vol. 2011 (2011), No. 99, pp. 1--8.\newline
ISSN: 1072-6691. URL: http://ejde.math.txstate.edu or http://ejde.math.unt.edu
\newline ftp ejde.math.txstate.edu}
\thanks{\copyright 2011 Texas State University - San Marcos.}
\vspace{9mm}}

\begin{document}
\title[\hfilneg EJDE-2011/99\hfil Reaction-diffusion systems]
{Global classical solutions for reaction-diffusion systems
with a triangular matrix of diffusion coefficients}

\author[B. Rebiai\hfil EJDE-2011/99\hfilneg]
{Belgacem Rebiai}

\address{Belgacem Rebiai \newline
Department of Mathematics and Informatics,
 Tebessa University 12002, Algeria}
\email{brebiai@gmail.com}

\thanks{Submitted January 16, 2011. Published August 7, 2011.}
\subjclass[2000]{35K45, 35K57}
\keywords{Reaction-diffusion systems; Lyapunov functional;
 global solution}

\begin{abstract}
 The goal of this article is to study the existence
 of classical solutions global in time for reaction-diffusion
 systems with strong coupling in the diffusion and with
 exponential growth (or without any growth) conditions on
 the nonlinear reactive terms. This extends some similar
 results in the case of a diagonal diffusion-operator associated
 with nonlinearities preserving the positivity and the total mass
 of the solutions or for which the total mass is a priori bounded.
\end{abstract}

\maketitle
\numberwithin{equation}{section}
\newtheorem{theorem}{Theorem}[section]
\newtheorem{proposition}{Proposition}[section]
\newtheorem{lemma}{Lemma}[section]

\section{Introduction}

In this study, we are interested in the existence of classical
global solutions to the reaction-diffusion system
\begin{gather} \label{e1.1}
\frac{\partial u}{\partial t}-a\Delta u=\lambda-f(u,v)-\mu u
\quad\text{in }  (0,+ \infty) \times \Omega , \\
\frac{\partial v}{\partial t}-c\Delta u-d\Delta v=f(u,v)-\mu v\quad
 \text{in } (0,+ \infty) \times \Omega, \label{e1.2}
\end{gather}
where $ \Omega $ is an open bounded domain of class $ C^1 $
in $\mathbb{R}^{n}$ with boundary
$\partial \Omega$, the constants $a, c, d, \lambda,\mu $ are such that
\begin{itemize}
\item[(A1)] $a>0$, $c>0$, $d>a$, $2\sqrt{ad}>c$, $\lambda \geq 0$
and $\mu>0 $,
\end{itemize}
and the function $f$ is a nonnegative and continuously differentiable
on $[0,+ \infty)$ such that
\begin{itemize}
\item[(A2)] $ f(0,\eta)=0 $ and $ f(\xi,\eta) \geq 0 $, with
 $ f(\xi,\frac{c}{d-a}( \frac{\lambda}{\mu}-\xi)) = 0 $ when
 $a+c \geq d$,
\item[(A3)]  $ f(\xi,\eta) \leq C \varphi(\xi)\eta^{r}e^{\alpha \eta} $
 for some constants $C >0$ and $\alpha >0$ when $a+c< d$,
where $r$ is a positive constant such that $r\geq 1$ and $\varphi$
is any nonnegative continuously differentiable function on
$[0,+ \infty)$  such that $\varphi(0)=0$.

\end{itemize}
We assume that the solutions of \eqref{e1.1}--\eqref{e1.2} also
satisfy: the boundary conditions
\begin{equation} \label{e1.3}
\frac{\partial u}{\partial \nu}=\frac{\partial v}{\partial \nu}=0
\quad \text{on }   (0,+ \infty) \times \partial \Omega ,
\end{equation}
where $\frac{\partial}{\partial \nu}$ is the outward normal
derivative to $\partial \Omega$;
and the initial conditions
\begin{equation} \label{e1.4}
 u(0,x)=u_{0}(x) ,\quad  v(0,x)=v_{0}(x)\quad\text{in } \Omega ,
\end{equation}
where $u_0$, $v_0$ are nonnegative and bounded functions
satisfying the following restrictions:
\begin{gather} \label{initialu}
\begin{gathered}
\|u_0\|_{\infty} \leq  \frac{\lambda}{\mu} < \frac{8ad}
 {\alpha n(a-d)^2} ,\quad\text{when } a+c < d,   \\
\|u_0\|_{\infty} \leq \frac{\lambda}{\mu},\quad\text{when }
 a+c \geq d,
\end{gathered}\\
\label{initialv}
v_0 \geq \frac{c}{d-a}( \frac{\lambda}{\mu}-u_0 ).
\end{gather}
Problem \eqref{e1.1}--\eqref{e1.4} may be viewed as a diffusive
epidemic model where $ u $ and $ v $ represent the nondimensional
population densities of susceptibles and infectives, respectively.
This problem can be represent a model describing the spread of
an infection disease (such as AIDS for instance) within a population
assumed to be divided into the susceptible and infective classes
as precised (for further motivation see for instance
\cite{cast,cuss,hama} and the references therein).

When $ \lambda = \mu = 0$, Kouachi and Youkana \cite{KY01} generalized
the method of Haraux and Youkana \cite{HY88} with the reaction
 term $f(\xi,\eta) $  requiring the condition
\begin{equation*}
\lim_{\eta \rightarrow +\infty }  \frac{\ln ( 1+f(\xi,\eta)) }
{\eta}<\alpha ^{\ast },\quad \text{for any } \xi \geq 0,
\end{equation*}
with
\begin{equation*}
\alpha ^{\ast }=\frac{2ad}{n( a-d)^{2}\| u_{0}\| _{\infty }}
\min \{ 1,\frac{a-d}{c}\} ,
\end{equation*}
where  $ a,\,c $ and $ d $ satisfy $ a>0$, $c>0$, $d>0 $ and $  a>d $.
 This condition reflects the weak exponential growth of the function
$f$.  \\
 Kanel and Kirane \cite{kaki} proved the  existence of a
classical global solutions for a coupled reaction-diffusion
system without any conditions on the growth of the function
$ f $ under the following conditions:
\begin{itemize}
\item $ a>d $ and $  c \geq d- a >0 $,
\item $ f(\xi,\eta) =F(\xi)G(\eta) $.
\end{itemize}
Later they improved their results in \cite{KKi00} where they extended
the result of Herrero et al \cite{HLV98} to the case of a bounded
domain under the following assumptions:
\begin{itemize}
\item $ a<d $ and $ 0 \leq c <d- a  $,
\item $ f(\xi,\eta) \leq C \varphi(\xi)e^{\alpha \eta} $,
for some $C >0$, $\alpha >0$ and any nonnegative continuous
and locally Lipschitzian function $\varphi$  on $ \mathbb{R} $
 such that $\varphi(0) = 0$.
\end{itemize}

In the case, where $\lambda \geq 0$ and $\mu > 0 $,
Abdelmalek and Youkana \cite{AbYo10} proved the global existence
of nonnegative classical solutions for the nonlinearities of
weakly exponential growth under the following assumptions:
\begin{itemize}
\item $a>0$, $c>0$, $d-a \geq c$, and $2\sqrt{ad}>c$,
\item  $\|u_0\|_{\infty} \leq \lambda/\mu$.
\end{itemize}

We note that solving problem \eqref{e1.1}--\eqref{e1.4} is quite
difficult. As a consequence of the blow-up examples found
in \cite{PS97}, we can prove that there is blow-up of the
solutions in finite time for such triangular systems even
though the initial data are regular, the solutions are positive
and the nonlinear terms are negative, a structure that ensured
the global existence in the diagonal case.

The aim of this article is to prove the existence of global
classical solutions to \eqref{e1.1}--\eqref{e1.4} without any
restrictions on the growth of the function $ f $ when $a+c \geq d$
and with possibility of exponential growth for this function
when $a+c < d$. For this purpose,  we demonstrate that for
any initial conditions satisfying \eqref{initialu}
and \eqref{initialv}, the problem \eqref{e1.1}--\eqref{e1.4}
is equivalent to a problem for which the global existence
follows from a similar Lyapunov functionals  appeared
in \cite{HY88,Ba94,KY01,RB09} under the assumptions
(A1)--(A3).

\section{Existence of local and positive solutions}

The study of  existence and uniqueness of local solutions $(u,v)$
of  \eqref{e1.1}--\eqref{e1.4} follows from the basic existence
theory for parabolic semilinear equations
(see, e.g., \cite{Am88,frie,henr,pazy}). As a consequence,
for any initial data in $C(\overline{\Omega})$
or $L^{\infty}(\Omega)$ there exists a $T^* \in (0,+\infty]$
such that \eqref{e1.1}--\eqref{e1.4} has a unique classical
solution on $ [0, T^*) \times \Omega $. Furthermore,
if $ T^* < +\infty $, then
$$
 \lim_{t\uparrow T^*} \big(\|u(t)\|_{\infty}+\|v(t)\|_{\infty}\big)
=+ \infty.
$$
Therefore, if there exists a positive constant $C$ such that
$$
\|u(t)\|_{\infty}+\|v(t)\|_{\infty} \leq C \quad
\forall t \in [0, T^*),
$$
then $T^*= +\infty$.

Since the initial conditions  \eqref{initialu}
and \eqref{initialv} are satisfied under assumptions (A1) and (A3),
the next lemma says that the classical solution of
\eqref{e1.1}--\eqref{e1.4} on $ [0, T^*) \times \Omega $
 remains nonnegative on $ [0, T^*)\times \Omega $.

\begin{lemma} \label{InvR}
Assume {\rm (A1), (A3)}.
Then for any initial conditions $ u_0 $ and $ v_0 $ satisfying
 \eqref{initialu} and \eqref{initialv}, the classical solution
$(u,v)$ of  problem \eqref{e1.1}--\eqref{e1.4} on
$ [0, T^*)\times \Omega $  satisfies
$$
0 \leq u \leq \frac{\lambda}{\mu}, \quad
v \geq \frac{c}{d-a}( \frac{\lambda}{\mu}-u) .
$$
\end{lemma}

\begin{proof}
In  system \eqref{e1.1}-\eqref{e1.2} the change of variables
\begin{gather*}
w = v - \frac{c}{d-a}( \frac{\lambda}{\mu}-u), \\
F(u,w)=f(u,w + \frac{c}{d-a}( \frac{\lambda}{\mu}-u))
\end{gather*}
leads to the system
\begin{gather} \label{e2.3}
\frac{\partial u}{\partial t}-a\Delta u
=  \lambda -F(u,w)-\mu u \quad\text{in }  (0,+ \infty) \times \Omega ,\\
\frac{\partial w}{\partial t}-d\Delta w=\frac{d-a-c}{d-a}F(u,w)
-  \mu w \quad\text{in } (0,+ \infty) \times \Omega , \label{e2.4}
\end{gather}
with  boundary conditions
\begin{equation} \label{e2.5}
\frac{\partial u}{\partial \nu}=\frac{\partial w}{\partial \nu}=0,\quad
\text{on }  (0,+ \infty) \times \partial \Omega ,
\end{equation}
and  initial conditions
\begin{equation} \label{e2.6}
 u(0,x)=u_{0}(x) ,\quad  w(0,x)=w_{0}(x)\quad\text{in } \Omega ,
\end{equation}

If we assume  (A1) and (A3), then a simple application of comparison
theorem \cite[Theorem 10.1]{smol} to system \eqref{e2.3}-\eqref{e2.4}
implies that for any initial conditions $ u_0 $ and $ v_0 $
satisfying \eqref{initialu} and \eqref{initialv},  we have
$$
0 \leq u(t,x) \leq \frac{\lambda}{\mu}, \quad
v(t,x)\geq \frac{c}{d-a}( \frac{\lambda}{\mu}-u(t,x))\quad
 \forall (t,x)\in  [0, T^*)\times \Omega .
$$
\end{proof}

\section{Existence of global solutions}

It is clear that to prove the  existence of global solutions for
problem \eqref{e1.1}--\eqref{e1.4} we need to prove it for
problem \eqref{e2.3}-\eqref{e2.6}.

At first, when $a+c \geq d$, the local classical solutions of
\eqref{e1.1}--\eqref{e1.4} may be extended as a classical and
uniformly bounded solutions on $[0, +\infty) \times \Omega $
for any nonnegative initial data $u_0$ and $v_0$
satisfying \eqref{initialu} and \eqref{initialv} without
any restrictions on the growth of the function $ f $ under
the assumptions (A1) and (A2).
Indeed, since  $u$, $w$ and $ f $ are nonnegative, then from (A1)
and (A2), we have by the comparison theorem that
$$
0 \leq u(t,x) \leq \frac{\lambda}{\mu}, \quad
0 \leq w(t,x) \leq \|w_0\|_{\infty} \quad \forall (t,x)\in
[0, T^*)\times \Omega .
$$
Now, the main result for the case $a+c < d$ is stated in the
following theorem.

\begin{theorem} \label{global}
Under  assumptions (A1)-(A3) and  restrictions \eqref{initialu}
and \eqref{initialv}, the solutions of
problem \eqref{e1.1}--\eqref{e1.4} are global and uniformly
 bounded on $[0, +\infty) \times \Omega $.
\end{theorem}

Since $ 0 \leq u \leq  \frac{\lambda}{\mu} $, then the problem
of global existence reduces to establish the uniform boundedness
of $w$ on $[0, T^*)$. By $L^p$-regularity theory for parabolic
operator (see, e.g., \cite{LSU68,Ro84}) it follows that it
is sufficient to derive a uniform estimate of
$\|\rho F(u,w)-\mu w\|_p$ on $[0, T^*)$ for some $p>\frac{n}{2}$
where $ \rho = \frac{d-a-c}{d-a} $.
The proof of Theorem~\ref{global} is based on the following key
proposition.

\begin{proposition} \label{Lyap}
Suppose {\rm (A1)-(A3)}, \eqref{initialu} and \eqref{initialv}.
 For every classical solution $(u,w)$ of \eqref{e2.3}-\eqref{e2.6}
on $ [0, T^*) \times \Omega $, consider the function
$$
 L(t)=\int_{\Omega}[\delta u+(M-u)^{-\gamma}(w+1)^{\beta p}
e^{\alpha pw}](t,x)dx,
$$
where $\alpha$, $ \beta $, $\gamma$, $\delta$, $p$ and $M$ are
positive constants such that
\begin{equation}
\label{Lyap1}
 \frac{\lambda}{\mu} < M<\frac{2\gamma}{\alpha n}, \quad
 \gamma< \overline{\gamma} =\frac{4ad}{(a-d)^2}, \quad
 \beta = \max \{r ,
\frac{\overline{\gamma}(1+\gamma)}{p(\overline{\gamma}-\gamma)} \}.
\end{equation}
 Then, there exists $\delta>0$, $ \sigma >0 $ and $p>\frac{n}{2}$
such that
 \begin{equation} \label{Lyap2}
\quad \frac{d}{d t}L(t) \leq -\mu L(t)+ \sigma \quad
\forall t \in [0, T^*).
\end{equation}
\end{proposition}

Before proving this proposition we need the following lemmas.

\begin{lemma} \label{Lyaplem1}
Let $(u,w)$ be a solution of \eqref{e2.3}-\eqref{e2.6} on
$ [0, T^*) \times \Omega $, then under  assumption (A3), we have
\begin{equation}
\label{Lyap3}
\int_{\Omega}F(u(t,x),w(t,x))dx \leq \lambda|\Omega|
-\frac{d}{dt} \int_{\Omega}u(t,x)dx.
\end{equation}
\end{lemma}

\begin{proof}
Since $ u $ is a nonnegative function,  it suffices to integrate
 both sides of \eqref{e2.3} on $ \Omega $, to obtain \eqref{Lyap3},
which competes the proof.
\end{proof}

\begin{lemma} \label{Lyaplem2}
Let $\phi$ and $ \psi $ be two nonnegative continuous functions
on $ [0, +\infty) $ with $\phi(\eta)$ goes to $ + \infty $ as
$\eta \rightarrow + \infty$.
Then there exists a positive constant $A $ such that
\begin{equation} \label{Lyap4}
\big( 1-\phi(\eta)\big)\psi(\eta) \leq A  \quad \forall \eta \geq 0.
\end{equation}
\end{lemma}

\begin{proof}
Since $\phi(\eta)$ goes to $ + \infty $  as
$\eta \rightarrow + \infty$, there exists $\eta_0 >0$
such that for all $\eta > \eta_0$, we obtain
$$
( 1-\phi(\eta))\psi(\eta) \leq 0.
$$
On the other hand, if $\eta$ is in the compact interval
$  [0,\eta_0]$, then the continuous function
$$
\eta \longmapsto \big( 1-\phi(\eta)\big)\psi(\eta)
$$
is bounded. So that \eqref{Lyap4} immediately follows.
\end{proof}

\begin{proof}[Proof of Proposition~\ref{Lyap}]
Differentiating $L$ with respect to $t$, one obtains
\begin{equation} \label{Lyap5}
\frac{d}{dt}L(t)= \delta \frac{d}{dt}\int_{\Omega}u(t,x)dx +I+J,
\end{equation}
where
\begin{align*}
 I & =  \int_{\Omega}\Big( a\gamma(M-u)^{-\gamma -1}(w+1)^{\beta p}
 e^{\alpha pw}\Delta u   \\
 & \quad +  d p(M-u)^{-\gamma}[\alpha (w+1)^{\beta p}
 + \beta (w+1)^{\beta p-1} ] e^{\alpha pw} \Delta w \Big)\,dx,
\end{align*}
and
\begin{align*}
 J & = \int_{\Omega}\mu \Big( \gamma (M-u)^{-1}
(\frac{\lambda}{\mu}-u) - p [ \alpha + \beta(w+1)^{-1}]w \Big)  \\
 &\quad\times (M-u)^{-\gamma}(w+1)^{\beta p}e^{\alpha pw}dx \\
 & \quad+ \int_{\Omega} \Big(  \rho p(M-u)
 [ \alpha + \beta(w+1)^{-1}] - \gamma \Big) \\
 &\quad  \times F(u,w) (M-u)^{-\gamma -1}(w+1)^{\beta p}
 e^{\alpha pw}dx.
\end{align*}
Using Green's formula in the first integral and taking into account
\eqref{e2.5}, we obtain
$$
I \leq -\int_{\Omega}Q(\nabla u, \nabla w)(M-u)^{-\gamma -2}(w+1)^{\beta p}e^{\alpha pw}dx,
$$
where
\begin{align*}
Q(\nabla u, \nabla w)
&=  a\gamma(1+\gamma)|\nabla u|^2+ \gamma p (a+b)(M-u)
 [ \alpha + \beta(w+1)^{-1}]\nabla u\nabla w \quad\ \\
 &\quad +   d p(M-u)^2 [\alpha ^2p +2 \alpha \beta p (w+1)^{-1}
 + \beta(\beta p-1) (w+1)^{-2} ] |\nabla w|^2,
\end{align*}
is a quadratic form with respect to $ \nabla u $ and $ \nabla w $.

The discriminant of $Q$ is given by
\begin{align*}
D&=\gamma p (d-a)^2 (M-u)^2 \Big( \beta [\beta p (\gamma -
\overline{\gamma}) + \overline{\gamma} (1+\gamma)](w+1)^{-2}\\
  \\
&\quad  + \alpha^2p (\gamma - \overline{\gamma})
[ \alpha +  2 \beta (w+1)^{-1}] \Big).
\end{align*}
 From conditions \eqref{Lyap1}, we have $ D \leq 0 $, then
we obtain $Q(\nabla u,\nabla v) \geq 0$ and consequently
\begin{equation}\label{Lyap6}
I \leq 0.
\end{equation}
Concerning the term $J$, since $0 \leq u \leq \frac{\lambda}{\mu} <M$,
we observe that
\begin{align*}
J  \leq \int_{\Omega}\mu \big( \gamma - p [ \alpha + \beta(w+1)^{-1}]w \big)
(M-u)^{-\gamma}(w+1)^{\beta p}e^{\alpha pw}dx  \\
 + (M-\frac{\lambda}{\mu})^{-\gamma -1}\int_{\Omega}
\big( pM [ \alpha + \beta(w+1)^{-1}] - \gamma \big)
 F(u,w) (w+1)^{\beta p}e^{\alpha pw}dx,
\end{align*}
or
\begin{align*}
J  &\leq - \mu L(t)+ \lambda \delta |\Omega |   \\
&\quad + \mu (M-\frac{\lambda}{\mu})^{-\gamma } \int_{\Omega}
 \big( \gamma +1- p [ \alpha + \beta(w+1)^{-1}]w \big)
 (w+1)^{\beta p}e^{\alpha pw}dx  \\
&\quad + (M-\frac{\lambda}{\mu})^{-\gamma -1}\int_{\Omega}
 [\beta pM - (\gamma - \alpha pM )(w+1)]  F(u,w)
 (w+1)^{\beta p-1}e^{\alpha pw}dx.
\end{align*}
From \eqref{Lyap1}, we obtain $\frac{n}{2}<\frac{\gamma}{\alpha M}$.
Then we can choose $p$ such that
$ \frac{n}{2}<p<\frac{\gamma}{\alpha M} $.
Using Lemma \ref{Lyaplem2}, we get $\delta_1>0$ and $\delta_2>0$
such that
$$
J \leq - \mu L(t)+ (\lambda \delta
 + \mu \delta_1 (M-\frac{\lambda}{\mu})^{-\gamma }) |\Omega |
 + \delta_2 (M-\frac{\lambda}{\mu})^{-\gamma -1}\int_{\Omega}F(u,w)dx.
$$
Let $\delta =\delta_2 (M-\frac{\lambda}{\mu})^{-\gamma -1}$ and
using Lemma \ref{Lyaplem1}, we obtain
\begin{equation}\label{Lyap7}
J \leq - \mu L(t)+  (2\lambda \delta
 + \mu \delta_1 (M-\frac{\lambda}{\mu})^{-\gamma }) |\Omega |
  -\delta \frac{d}{dt} \int_{\Omega}u(t,x)dx.
\end{equation}
From \eqref{Lyap6} and \eqref{Lyap7}, we conclude that
$$
\frac{d}{dt}L(t) \leq - \mu L(t)+ \sigma ,
$$
where $ \sigma = (2\lambda \delta
 + \mu \delta_1 (M-\frac{\lambda}{\mu})^{-\gamma }) |\Omega | $.
This concludes the proof.
\end{proof}

\begin{proof}[Proof of Theorem~\ref{global}]
 Let $p$ be the same as in Proposition~\ref{Lyap}.
 Since $M^{- \gamma} \leq (M-u)^{-\gamma}$,
from \eqref{Lyap1} and (A3) it follows that
\begin{gather*}
 \|w\|_p^p  =  \int_{\Omega}|w|^pdx \leq M^{\gamma}L(t),\\
 \|F(u,w)\|_p^p  =  \int_{\Omega}|F(u,w)|^pdx \leq M^{\gamma}K^pL(t),
\end{gather*}
where
$$
K= \max_ {0\leq \xi \leq \frac{\lambda}{\mu}}\, \varphi(\xi).
$$
By  \eqref{Lyap2}, it is seen that there exists a positive constant
$ B $ such that
$$
L(t) \leq B \quad \forall t \in [0, T^*),
$$
and consequently
\begin{gather*}
\|w\|_p^p  \leq BM^{\gamma},\\
\|F(u,w)\|_p^p  \leq  BM^{\gamma}K^p.
\end{gather*}
Hence $\rho F(u (t,.),w (t,.))- \mu w (t,.)$ is uniformly bounded
in $L^p(\Omega)$ for all $t \in [0,T^*)$ with $p>\frac{n}{2}$.
Using the regularity results for solutions of parabolic
equations in \cite{LSU68,Ro84}, we conclude that the solutions
of the problem \eqref{e1.1}--\eqref{e1.4} are uniformly bounded
 on $ [0, +\infty) \times \Omega $.
\end{proof}

\subsection*{Acknowledgements}
The author would like to thank Professor M. Kirane and the anonymous
referees for their useful comments and suggestions that helped
improving the presentation of this article.

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